Ma waho aʻe o ka hoʻololi ʻana i ka nohona a me ka mālama ʻana i nā maʻamau maikaʻi, ʻo ka hoʻohui exogenous o nā mea kūlohelohe anti-aging he ala maʻalahi a maʻalahi hoʻi ka anti-aging. Wahi a ke kuhikuhi noiʻi (NAD + metabolic regulation) a me nā hopena noiʻi anti-aging i kēia manawa a me nā noi e pili nui ana.hoi ka"ʻohu lolo"ma hope o COVID-19,makou'makemake wau e hoʻolauna i kekahi mau mea maikaʻimea kūʻē i ka wā kahikomai nā mea kūʻai kūʻai wela ma Amazon.
1. Nā mea hoʻohui NAD+ (NMN, NR, NADH)
Ke emi nei nā pae NAD+ me ka makahiki, e alakaʻi ana i ka degeneration e pili ana i nā pae NAD+. ʻAʻole hiki i ka ʻohana acetylase (sirtuins, hoʻolaha pinepine ʻia e like me nā protein lōʻihi) ke mālama i ka hana maʻamau, no laila ʻaʻole hiki ke hoʻokō ʻia nā hana he nui e pono ai ke olakino i hoʻopili ʻia e sirtuins, ʻo ia kekahi o nā kumu nui o ka ʻelemakule.IʻO ka lawe ʻana o NMN (nicotinamide mononucleotide), NR (nicotinamide riboside) a i ʻole NADH (nicotinamide adenine dinucleotide) hiki ke kōkua i nā cell e hoʻonui i nā pae NAD +, a aia kēia mau mea i nā cell a me nā meaʻai maoli..I kēia manawa, aia nā haneli o nā noiʻi lapaʻau ma NMN, NR, a me NADH, e kālele ana i nā ʻano like ʻole e like me ka anti-aging, diabetes, metabolism, a me ka cognition.
2. Pyrroloquinoline quinone (PQQ)
ʻO PQQ kahi coenzyme redox a me kahi antioxidant ikaika. Aia nō ma nā meaʻai like ʻole. He haʻahaʻa loa ka ʻike o ka PQQ i ke kino o ke kanaka. Hiki mai ka PQQ i loko o nā pūnaewele kanaka mai ka meaʻai a i ʻole nā microorganism. ʻO nā meaʻai me ka PQQ hou aʻe: natto, pāhiri, kī ʻōmaʻomaʻo, hua kiwi, papaya, tofu, a pēlā aku. Hiki i ka PQQ ke hoʻoulu i ka biosynthesis mitochondrial a he mea hoʻoulu i nā sirtuins. ʻO nā pōmaikaʻi olakino kūpono o ka PQQ: ka hoʻomaikaʻi ʻana i ka hiamoe, anti-diabetes, anti-arthritis, anti-osteoporosis, hōʻemi i ka ʻeha cardiac ischemia-reperfusion, inhibiting tyrosinase, hoʻomaikaʻi i ka momona.
3. Fisetin
ʻO Fisetin, i ʻike ʻia ʻoWehe Laau Uhi , he flavonol i loaʻa i ka mea kanu a me ka puaʻa mea kanu maʻamau i loaʻa i loko o nā mea kanu maʻamau a me nā huaʻai e like me nā strawberries, nā ʻāpala, nā persimmons, nā aniani, a me nā kukama. Hoʻonui ia i ke ola o nā ʻiole kahiko e 10%, hoʻemi i nā hōʻailona ʻelemakule i loko o nā ʻiʻo, a hoʻolohi i nā maʻi pili i ka ʻelemakule. ʻO ka hana anti-aging o fisetin hiki iā ia ke wehe i nā cell senescent a hana ma ke ʻano he synolytic. ʻO ka hōʻiliʻili ʻana o nā cell senescent kekahi kumu nui o ka ʻelemakule a me nā maʻi pili i ka ʻelemakule. Ua ʻike nā haʻawina ʻo nā pono olakino hiki ke loaʻa i ka fisetin: anti-oxidation, anti-inflammation, pale puʻuwai, pale cognitive, pale i ka momona a me nā maʻi metabolic.
4. Urolithin A
Aia ka Urolithin A i loko o nā ʻiʻo like ʻole o ke kino kanaka. Akā ʻo ka urolithin A ʻaʻole ia he mole kūlohelohe i ka meaʻai a ua hana ʻia e kekahi mau maʻi bacteria e hoʻoheheʻe i ka ellagic acid a me nā ellagitannins. Loaʻa nā precursors o ka urolithin A - ellagic acid a me ellagitannins - i nā meaʻai like ʻole, e like me nā pomegerane, nā strawberries, nā raspberries, a me nā walnuts. Hiki i ke kino o ke kanaka ke hana i ka urolithin A ma hope o ka ʻai ʻana i kēia mau precursors ua kaupalena ʻia e ka ʻokoʻa o nā microorganisms intestinal. Ke alakaʻi nei ka ʻelemakule i ka emi ʻana o ka hiki autophagic o nā cell, kahi e alakaʻi ai i ka hōʻiliʻili ʻana o ka mitochondria pōʻino, hoʻoulu i ke koʻikoʻi oxidative, a hoʻoulu i ka mumū. Hoʻomaikaʻi ʻo Urolithin A i ke olakino mitochondrial ma o ka hoʻonui ʻana i ka autophagy.
5. Spermidine
ʻO ka Spermidine he polyamine maoli nona ka emi ʻana o ka intracellular i ka wā ʻelemakule o ke kanaka, a aia paha kahi loulou ma waena o ka emi ʻana o ka spermidine a me ka degeneration pili i ka makahiki. .ʻO nā hopena kūpono o ka spermidine: hoʻohaʻahaʻa i ke koko, hoʻonui i ka pale antioxidant, hoʻonui i ka bioavailability arginine, hoʻemi i ka mumū, hoʻemi i ka paʻakikī vascular, hoʻoponopono i ka ulu ʻana o ka cell.
Ka manawa hoʻouna: Mar-02-2023
