Hana nui e pili ana iā Spermidine a me Spermidine trihydrochloridecan i ka noiʻi

Hana nui e pili anaSpermidine aSpermidine trihydrochloridehiki i ka noiʻi

ʻO Spermidine [N-(3-aminopropyl) -1,4-diaminobutane] he triamine linear saturated i helu pinepine ʻia ma ke ʻano he waena i ka synthesis o ka spermine. Loaʻa iā ia ka molecular formula C1H19N3 a me ka molar mass 145.25 g / mol a he liʻiliʻi, hiki ke hoʻoheheʻe ʻia i ka wai, amphiphilic mole me ka hiki ke komo i nā membrane biological. Loaʻa ia ma nā mea ola he nui, me ka nānā ʻole i ka hoʻokaʻawale ʻauhau.

Hiki i ka Spermidine ke hoʻopaʻa i nā ʻano molekole like ʻole, e hoʻohana pono iā lākou. Kākoʻo lākou i nā kaʻina hana e pili ana i ka ulu ʻana o ka cell, ke kūpaʻa DNA, ka hoʻonui ʻana o ka cell a me ka apoptosis. ʻIke ʻia ka hana like ʻana o nā polyamines me nā mea ulu i ka wā o ka māhele cell. ʻO ia ke kumu he mea nui ka spermidine no ka ulu a me ka hana o ke kino.

1. Nā waiwai anti-inflammatory o Spermidine no ka maʻi kanesa a me ke olakino cardiovascular

Ma kahi noiʻi 2016, ua ʻike ʻia ka spermidine e hoʻohuli i ka uaki kahiko a hoʻomaikaʻi i ka hana cardiovascular i nā ʻiole kahiko. Ma ka pae okana, hoʻomaikaʻi ʻia ke ʻano o ka naʻau a me ka hana i nā ʻiole kahiko i hāʻawi ʻia i ka spermidine. Ua hoʻomaikaʻi hou ʻia ka Metabolism i kēia mau ʻiole ma muli o ka hoʻihoʻi ʻana o ke ʻano mitochondrial a me ka hana ma hope o ka spermidine supplementation.

2. Spermidinee hana ana ma ke ano he anti-ʻelemakule mea ʻai

Ma ke ʻano o ka lōʻihi, ua hōʻike ʻia nā haʻawina holoholona he nui i ka lawe ʻana i ka spermidine e hoʻonui i ke ola a pale i ka fibrosis ate a me ka maʻi hepatocellular carcinoma. ʻO ka mea like me ka meaʻai momona polyamine. Aia kekahi mau hōʻike e hoʻonui ai i ke kū'ē i ke kaumaha, a ʻo ka emi ʻana o ka makahiki o ka spermidine e kākoʻo i ka ulu ʻana o ka maʻi pili makahiki.

3.Spermidine trihydrochloridehiki rhoʻonaʻauao i ka hoʻemi ʻana o ka naʻau

ʻO ka noiʻi i paʻi ʻia ma ka puke moʻolelo Cell Reports ma 2021 nā kikoʻī e hoʻomaikaʻi ka spermidine meaʻai i ka cognition a me ka hana mitochondrial i nā nalo a me nā ʻiole, a hāʻawi i kekahi mau ʻikepili kanaka.