Lo Han GuoʻO ka extract he pauda melemele ʻeleʻele a hiki i ka ʻāpana ʻeleʻele. He ʻono loa ia, he 240 manawa ʻoi aku ka ʻono ma mua o ka sucrose, kokoke i ke kō, me kahi ʻono licorice-like. ʻO ka helu heheʻe o ka mogroside maʻemaʻe kiʻekiʻe he 197-201°C. Hiki ke hoʻoheheʻe ʻia i ka wai a me ka ethanol.
Hana:
1.Hua MonekaHoʻohana ʻia (Mogroside) i ka lāʻau lapaʻau Kina kuʻuna no ke anu, ka ʻāʻī, ka ʻeha ʻāʻī, ka ʻeha o ka ʻōpū, a hiki ke hoʻohana ʻia e hoʻomaʻemaʻe i ke koko.
2. He maʻalahi ka hoʻoheheʻe ʻia o ka Monk Fruit Extract (Mogroside) i ka wai a ʻaʻohe ua.
3. Loaʻa i ka Mogroside ka nui o nā amino acids, fructose, nā huaora a me nā minela. Hoʻohana ʻia ia i ka kuke kuʻuna Kina ma ke ʻano he mea ʻala a me ka meaʻai meaʻai. Ma ke ʻano he mea ʻono kūlohelohe honua, he mea kūpono ia no nā mea ʻono artificial e like me aspartame. Hiki ke hoʻohana ʻia i loko o nā mea inu, nā meaʻai i kālua ʻia, nā meaʻai meaʻai, nā meaʻai haʻahaʻa-calorie a i ʻole nā meaʻai ʻē aʻe e koi ana i nā mea momona haʻahaʻa a i ʻole nā calorie haʻahaʻa a ʻaʻole ʻole. ʻAʻole pili ka kuke ʻana a i ʻole ka kuke ʻana i kona ʻono a i ʻole ka ʻono.
Nā hopena lāʻau lapaʻau
(1) Ka hopena expectorant: Mogroside (ka nui glycosides> 80%) 0.2g/kg, 0.4g/kg, 0.8g/kg i lawelawe intragastrially. ʻO nā doses o 0.4g / kg a me 0.8g / kg i hoʻonui nui i ka nui o nā mea huna tracheal i nāʻiole, e hōʻike ana i kahi hopena expectorant nui.
(2) Ka hoʻomaʻemaʻeʻana i ka māmā a me ka hopena antitussive: ʻO Mogroside (ka nui o nā glycosides> 80%) 0.2g/kg, 0.4g/kg, 0.8g/kg i hoʻemi nui i ka nui o nā ʻū i nā ʻiole i hoʻoulu ʻia e ka amonia, akā ʻaʻohe hopena koʻikoʻi ma luna. ka wā incubation o ka ʻū i hoʻokomo ʻia i ka ammonia.
(3) ʻO ka hoʻopau ʻana i nā radical manuahi a me nā hopena antioxidant:
a.Mogroside extract(Mogroside) (ka nui glycosides ≥ 98%, Mogroside V maʻiʻo 65.20%) i kekahi scavenging hopena ma hydroxyl noa radicals a me superoxide anion manuahi radicals. Me ka piʻi ʻana o ka hoʻonui ʻana o ka Mogroside extract, piʻi mālie ka hopena scavenging, e hōʻike ana i kahi pilina hopena-hopena;
b. He hopena koʻikoʻi ko ka Mogroside extract i ka hopena hemolysis oxidative o ka ʻiole RBC i ka wā o ka incubation in vitro. Ma ka laulā o 0.04-1.15 mg / ml, ka inhibition rate o Mogroside extract ma erythrocyte autooxidative hemolysis ua oi aku ma mua o 50%, a me Mogroside extract i ka maikaʻi palekana hopena ma RBC autooxidative hemolysis;
c. ʻO ka hopena pale o Mogroside extract ma RBC autooxidative hemolysis ʻaʻole hōʻike i kahi pilina hopena. ʻO ka hapa maikaʻi loa he 0.46 mg / ml, me ka nui o ka inhibition o 85.55%;
d. ʻO Malondialdehyde (MDA) ka hopena hope o ka lipid peroxidation a hiki ke hoʻohana ʻia e loiloi i ka ikaika o ka lipid peroxidation. Loaʻa i ka Mogroside extract kahi hopena paʻa paʻa i ka hana ʻana o MDA i ka wā erythrocyte autooxidation hemolysis;
a.Mogroside extractHe hopena maikaʻi ka pale ʻana i ka hana kūʻokoʻa o MDA i ka homogenate ate ʻiole. ʻOi aku ka maikaʻi o ka hopena inhibitory ma kahi o 0.875 mg / ml, hiki i ka 23.63%; f. Hiki i ka Mogroside extract ke kāohi i ka lipid peroxidation i loko o ka ʻiole o ke akepaʻa, he hopena pale i ka pōʻino o ka ate a me ka H2O2, a hiki ke hōʻemi i ka hopena o ka hemolysis erythrocyte; Hiki i ka Mogroside ke pale nui i ka hana ʻana o MDA i loko o ka mitochondria ate, a piʻi aʻe ka nui o ka inhibition me ka piʻi ʻana o ka noʻonoʻo.
(4) Hoʻonui i ka palekana:
ʻO ka hoʻoponopono waha o ka mogroside i nāʻiole maʻamau a me ka cyclophosphamide (CTX) -ʻaʻohe hopena koʻikoʻi i ka hana immune o nāʻiole maʻamau, akā ua hoʻomaikaʻi nui i ka macrophage phagocytosis a me ka hoʻonuiʻana o T cell o nāʻiole i kāohiʻia e CTX. Hōʻike kēia i ka mogroside he hopena hoʻoponopono maikaʻi i ka hana pale pale o nā ʻiole CTX-suppressed.
(5) Ka hopena i ke kō koko:
ʻAʻohe hopena koʻikoʻi o ka hoʻohana waha hoʻokahi o 30% mogroside 200 mg/kg i ke kō koko koko a me ka hana enzyme ate o nā pākeke olakino.MogrosideHe mea ʻono palekana ʻo V ʻaʻole pili i ke kō koko koko o nā kānaka maʻamau.
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(6) Ka hopena anti-cancer:
Me ka hoʻohana ʻana i ka DMBA ma ke ʻano he mea hoʻomaka a me ka TPA ma ke ʻano he carcinogen, ua mālama ʻia kahi hoʻokolohua carcinogenicity ʻelua o ka ʻiole; ʻO ka carcinogenicity lōʻihi o ka mogroside ua like a ʻoi aku ka ikaika ma mua o ka stevioside, e hōʻike ana he hopena anti-cancer. No laila, hiki ke hoʻohana ʻia ka mogroside ma ke ʻano he anti-cancer agent.
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Ka manawa hoʻouna: ʻAukake-23-2024
